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Several recent studies employing this methodology have uncovered that traditional memory-enhancing formulas regulate PI3K/AKT, Nrf2, MAPK, and NF-B pathways key nodes in the AD signaling network ( 2.5.1 Multi-omics approaches and systems biology in Alzheimers research Recent advances in multi-omics technologiesincluding transcriptomics, metabolomics, proteomics, and spatial transcriptomicshave opened new avenues for elucidating the molecular mechanisms through which natural products influence AD pathogenesis (Ma et al., 2024a)

Blood was collected at the indicated time points for antibody detection in the serum

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Material Potassium iodide, 2-hydrazinylpyridine, hydroquinone, 3-bromo-1-propanol, ruthenium (III) chloride hydrate, -terpinene, ammonium hexafluorophosphate, 2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9-hexadecafluorodecane-1,10-diol, 1,2,4,5-cyclohexanetetracarboxylic dianhydride, mPEG 5000 -OH, pyridine hydrofluoride, acetone, and mercaptoacetic acid were obtained from Aladdin (Shanghai, P