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deuteriujm bonds are stronger than hydrogen bonds, resulting in a slower rate of metabolism, (slower clearance), and longer half life, which reduces the dosing rate from 3 times a day to 2 times a day (Schneider et al, 2021)

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We conducted X-ray diffraction experiments and MD simulations for structural elucidation of the different TRaQ-G adducts to gain mechanistic insight into the varying GSH sensitivities of the molecules

Primary hepatocytes were incubated with combinations of primary antibodies against Drp1 (1:1000) and ACSL4 (1:1000), ACSL4 (1:1000) and COXIV (1:1000), or Drp1 (1:1000) and COXIV (1:1000)