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Patients with IBS can be categorized into four major subtypes depending on the predominant stool pattern, including IBS with constipation (IBS-C), IBS with diarrhea (IBS-D), IBS with mixed bowel habits (IBS-M) and unclassified IBS (Lacy et al., 2016)

Drakovi BM, Bogdanovi GA, Neelakantan MA, Chamayou AC, Thalamuthu S, Avadhut YS, Schmedt Auf Der Gnne J, Banerjee S, Janiak C: N-o-vanillylidene-l-histidine: experimental charge density analysis of a double zwitterionic amino acid schiff-base compound