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Inclusion criteria consisted of newly diagnosed, pathologically confirmed epithelial ovarian cancer, an age of 18 years or older, the ability to provide informed consent, willingness to provide access to medical records, undergoing interval or primary debulking surgery at UPMC/HCC, completing a full course (six cycles) of platinum-based chemotherapy at UPMC/HCC and willingness to provide biospecimens for banking purposes

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However, the BHMT reaction is limited to the human liver and kidney since BHMT is expressed primarily in the hepatocytes and kidney cortex (Sunden et al., 1997)

Diabetes Obesity and Metabolism , 25 (12), 37663778.