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Description

In a study by Vanderhoof et al., 41 oral erythromycin (20 mg/kg/day) was tried to patients with CVS as a prokinetic agent, which was suggested to be effective in some patients, but the efficacy was not confirmed due to poor quality of the study

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This article aims to review the research progress on key scientific issues such as the dynamic plasticity of T-cell exhaustion states, the heterogeneity boundary between exhaustion and dysfunction, and microenvironment-driven epigenetic reprogramming