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It is primarily investigated for its role in glucose-dependent insulin secretion, appetite signaling pathways, and energy balance regulation

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None of these theories has been substantiated by scientific research.[1,2] Despite proponents claims of recovery rates as high as 70% to 90%, case reviews by the National Cancer Institute (NCI) and the New York County Medical Society found no evidence of usefulness for the Gerson diet.[3] An NCI-sponsored study of Gonzalez therapy, which is similar to the Gerson diet, showed that patients with inoperable pancreatic adenocarcinoma who underwent standard chemotherapy with gemcitabine (Gemzar) survived three times longer and had better quality of life than those who chose enzyme treatment, which included pancreatic enzymes, nutritional supplements, detoxification, and an organic diet.[4] ADVERSE REACTIONS: Adverse reactions to the Gerson regimen include flu-like symptoms, loss of appetite, perspiration with foul odor, weakness, dizziness, cold sores, fever blisters, high fever, tumor pain, intestinal cramping, diarrhea, and vomiting