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March 8, 2017

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The liquor is mixed by aeration devices (supplying also oxygen) A portion of the biological sludge separated from the secondary effluent by sedimentation is recycled to the aeration tank Types of AS Systems: Conventional, Complete-Mix, Sequencing Batch Reactor, Extended Aeration, Deep Tank, Deep Shaft Advantages Flexible, can adapt to minor pH, organic and temperature changes Small area required Degree of nitrification is controllable Relatively minor odor problems Disadvantages High operating costs (skilled labor, electricity, etc.) Generates solids requiring sludge disposal Some process alternatives are sensitive to shock loads and metallic or other poisons Requires continuous air supply Advantages/Disadvantages Trickling Filters The trickling filter or biofilter consists of a bed of permeable medium of either rock or plastic Microorganisms become attached to the media and form a biological layer or fixed film

In contrast to EAE where the primary stimulus is immune upregulation in the presence of extrinsic myelin antigens, the CAE model illustrates that MS-like pathology can also be generated by an upstream intrinsic myelin injury, releasing antigens which secondarily trigger white matter inflammation in an immune-predisposed host