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Anim Sci J 91:e13357

378397 in the activation segment, including salt bridges between Glu379 from one protomer and Arg216 and Arg241 of the other protomer 8

While these reports highlight lower circulating glycine as an emerging biomarker for both NAFLD/NASH and ASCVD, studies in humans and mice support a causative role of reduced glycine availability and the potential of glycine-based treatment in both diseases (199, 201)