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Lack of Comprehensive Human Trials Most clinical trials for AOD 9604 have been small or short in duration

Secondary metabolic markers include fasting glucose, insulin sensitivity via HOMA-IR or glucose tolerance testing, body composition changes (DEXA scan or MRI for fat mass and lean mass distribution), mitochondrial respiration capacity via Seahorse analyzer, and serum markers like HbA1c for long-term glucose control

The isolated RNA was quantified spectrophotometrically using the A260/A280 ratio

5-Amino-1MQ is dosed at 2550 mg/kg, most commonly via oral administration due to its small molecular weight and decent oral bioavailability