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A lower dose of 17 (2.5 ug/ml) displayed a higher effect on the cell viability under 640 nm-30mW

doi: 10.1073/pnas.2009201117 27 KraftVANBezjianCTPfeifferSRingelstetterLMullerCZandkarimiFet al

Organic selenium compounds constitute a diverse array of molecules that can be categorized into distinct families based on their functional chemical structures: Selenides/diselenides, selenocyanates, selenoamino acid derivatives (e.g., SeMet and MSC), methyl selenoic acid (MSA

Importantly, we demonstrated that the ectopic expression of PLK2, independent of its kinase activity, in several types of cancer cells promoted the caspase-3 processing, GSDME cleavage, DAMPs release, and cell death, albeit without IL-1 secretion