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[4] Osteoarthrtitis pain [edit] As of 2012, the evidence was inconclusive as to whether SAM can mitigate the pain of osteoarthritis

40 Not only are OHCs exquisitely sensitive to the initial effects of acoustic overstimulation, which makes them excellent indicators of sound-induced ultrastructural damage, but also the final common pathway of the descending auditory-efferent system preferentially innervates the OHCs