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The lack of AMPK inhibits the repair of intestinal epithelial cells (Olivier et al., 2022), and AMPK has been identified as a drug target for alleviating inflammatory bowel disease (IBD) in a rabbit model (Hwang et al., 2019)

It should be noted that although NSDR may support relaxation and recovery, it still does not fully replicate the restorative effects of sleep, which are critically important for multiple biological processes, and for healthy aging in general

Symptomatic aged 5xFAD mice presented an expansion in both circulating CD4 + and CD8 + T Naive cells, and a contraction of the T EM pool, relative to WT mice (Supplementary Fig

The specific mechanisms remain under investigation, but the finding adds another dimension to DSIP's systemic regulatory effects