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It also mitigates the inflammatory response, leading to a decrease in the formation of reactive oxygen species (ROS) [85]

QTc Prolongation: QT studies with buprenorphine products have demonstrated QT prolongation 15 msec

Curtis AM, Seo SB, Westgate EJ, Rudic RD, Smyth EM, Chakravarti D, et al

Since the effectiveness of these other long-acting forms of HIV prevention has not yet been proven, they have not been considered for approval by the FDA