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Here, we developed novel tumor models for acquired resistance to anti-VEGF therapy by expressing a fusion protein of the mouse VEGFR2 extracellular domain and human IgG4 fragment crystallizable (Fc) region (VEGFR2-Fc) in Renca mouse renal cell carcinoma and B16F10 mouse melanoma cell lines

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Alternative treatment of polycystic ovary syndrome: pre-clinical and clinical basis for using plant-based drugs