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Causes of Insomnia Stress and Anxiety : Elevated stress and anxiety levels trigger the release of cortisol, a stress hormone, impacting the bodys ability to relax and enter a restful state, consequently hindering the initiation of sleep

NUTM2A-CIC fusion small round cell sarcoma: a genetically distinct variant of CIC-rearranged sarcoma

Neurological Damage: Prolonged vitamin B12 deficiency, especially if left untreated, can lead to irreversible neurological damage, including demyelination of nerve fibers in the brain and irreversible neurological deficits

Some reports have indicated that altered FSH-signaling and/or over expression of FSHR can actually promote apoptosis in unselected follicles, which may potentially happen via excessive accumulation of cAMP or activation of p38 MAPK pathways (106, 135)