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Also, in the experiments on human breast cancer cells, Won and Seo found that the inactivation of PI3K/Akt/mTORC1 signaling pathway promotes the expression of caspases and Bax leading to increased apoptosis [302]

HTY has been reported to reduce oxidation of low-density lipoprotein (LDL) cholesterol, which is considered an important contributing factor in atherosclerosis development

3.1 Inherited cerebellar ataxia Inherited Cerebellar Ataxias (ICAs) combine a group of complex and uncommon neurodegenerative conditions that impact the cerebellum, spinal cord, and peripheral nerves (Koeppen, 2005)