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Clin Med 16:104109

It appears to reset pathological gene expression, with observed effects on restoring function in dysfunctional systems

doi:10.1152/ajpheart.2000.279.4.H1540 7

The PubMed search also revealed that the pioneering use of transferrin receptor ligands for brain-targeting nanoparticle drug delivery systems was reported in 1996 by Huwyler et al