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David Wagner Key benefits of the findings: The use of the novel peptide was successful in preventing and reversing diabetes in mice, and the peptide was not shown to bind to unrelated or unintended molecules, reducing the risk of side-effects The treatment developed in mice may be successful in humans due to the similarity of the molecules involved

Therefore, targeting the HIF signaling pathway and its regulated downstream gene expression has become a potential strategy for treating hypoxia-related diseases

& Campos-Sandoval, J

In contrast to octahedral coordination geometries, trigonal prismatic coordination (and distorted versions thereof) are rare and occur mostly for d 0 , d 1 , and d 2 configurations