glutathione scholar in Skin Aging and Tissue Regeneration: A Systematic Review of Molecular Mechanisms, Redox Modulation, and Biomedical Implications The Role of Glutathione Metabolism

Despite these improvements, significant diagnostic delays persisted, particularly those patients with predominantly nonmotor or atypical symptoms [50]

Because glutamine is the source of -KG, glutaminase inhibitors such as BPTES interfere with -KG homeostasis and lead to inhibited proliferation in cancer cells carrying this mutant IDH1 (Seltzer et al., 2010)

Chen B, Zhao L, Yang R, Xu T

The clinical challenges associated with NSCLC, such as metastatic spread and therapeutic resistance, underscore the need for novel approaches to treatment, including those that address the underlying biology of the disease [3,4,5]