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On the other hand, Nanoreactors can intelligently activate multienzyme cascade reactions at high sugar levels to produce acidic substances such as gluconic acid (GA) and hydrogen peroxide, leading to the release of nitric oxide (NO), which can combat bacterial infection and inflammation in chronic wounds of diabetes

BSO-induced NO accumulation (detected at 14 h after exposure to 8 M BSO) was modestly reduced by joint treatment of cells with cPTIO (200 M) (Fig

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