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For tumors located near the brain or with potential brain metastases, careful consideration of treatment volumes is essential to avoid unnecessary radiation to the brain [94,95,96]

Epidemiological evidence suggests that intake exceeding 63 g of alcohol per day may correlate with a higher incidence of the disease [9]

Andrologia 53(1):e13577 Nogus MR, Giralt M, Romeu M, Mulero M, Snchez-Martos V, Rodrguez E, Acua-Castroviejo D, Mallol J (2006) Melatonin reduces oxidative stress in erythrocytes and plasma of senescence-accelerated mice

In addition, while sultam skeletons generally displayed slightly reduced reactivity towards amine-capping than other skeletons, they had notably reduced reactivity across all seven stereoisomers in the panel towards acylation compared to sulfonylation and reductive amination