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(2009) provided the foundation for the division of asthma into T2-high and T2-low endotypes based on gene expression patterns, identifying a T2-high gene signature characterized by elevated expression of IL-5, IL-13, and periostin in bronchial biopsies, which correlated with eosinophilic inflammation and response to corticosteroids

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L-carnitine supplementation attenuates NAFLD progression and cardiac dysfunction in a mouse model fed with methionine and choline-deficient diet