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Indeed, melatonin is highly permeable to cell membranes and easily crosses the bloodbrain barrier 51 , ensuring a good therapeutic profile for brain diseases, and is also able to accumulate into mitochondria, probably via GLUT/SLC2A and PEPT1/2 carriers 52,53

Here we review the mechanisms that regulate potassium homeostasis and describe the important role that the circadian clock exerts on these processes

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Increased nuclear apoptosis-inducing factor after transient focal ischemia: a 12/15-lipoxygenase-dependent organelle damage pathway