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It is worth noting that we further stratified diabetes based on obesity status since obesity is a common and metabolically significant comorbidity in diabetes, and its presence may influence both PA levels and their associations with different disease status

However, if darkening is velvety in texture, affects skin folds in multiple areas, and has appeared alongside weight gain, it may be a sign of acanthosis nigricans a condition associated with insulin resistance

A meta-analysis of the relationship between vaginal microecology, human papillomavirus infection and cervical intraepithelial neoplasia