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Base-called fast5 nanopore direct RNA sequencing data have been deposited at ENA under the accession PRJEB61652

In vivo proof of a powerful proinflammatory mechanism and a new anti-inflammatory strategy

In a pilot study in Thailand, Sangsuwan and Asawanonda tested the influence of daily intake of oral collagen (5 g) for 4 weeks on skin elasticity, especially in sun-exposed areas, in a randomized, double-blind, placebo-controlled trial (in a total of 36 women, aged 4060 years, where one-half of the participants were in the treatment group [ n = 18] or the placebo group [ n = 18]) [39]

Although transcriptomics and metabolomics provide valuable insights, experimental validation through in vivo functional studies is limited