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Discovery of an orally active small-molecule irreversible inhibitor of protein disulfide isomerase for ovarian cancer treatment

Cue-induced reinstatement test In the same self-administration context, the number of nosepoke into the active and inactive operanda was measured over 1 h

doi: 10.1016/j.pharmthera.2007.09.008, 109

Under normal conditions, glutathione levels are tightly regulated to ensure both adequate antioxidant capacity and controlled metabolic flux through its biosynthetic pathway