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The thioredoxin-1 inhibitor Txnip restrains effector T-cell and germinal center B-cell expansion

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Interventions with specific lactate-producing strains, such as Levilactobacillus brevis and Lactobacillus paracasei , have been shown to counteract this dysbiosis by increasing the abundance of SCFA-producing bacteria and reducing pro-inflammatory cytokines, thereby restoring a healthier microbial ecosystem and alleviating colitis [247, 248]

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