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Stimulated secretion of sIgA as a local defense mechanism can confirm this hypothesis, but more detailed studies about intestinal epithelial integrity and immunity are needed to extend knowledge regarding the complexity of microbiological, physiological and immunological processes in the gut

Therefore, neurotransmitter dysfunctions take part in the pathophysiology of ASD [53]

-HB suppresses activation of the NOD-, LRR- and pyrin domain-containing protein 3 (NLRP3) inflammasome by preventing K + efflux and reducing apoptosis-associated speck-like protein with caspase-recruitment domain (ASC) oligomerization and speck formation 78

It is not an FDA approved medication, but it is made in pharmacies that are FDA approved and regulated