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For example, p53 stabilization results in down-regulation of numerous metabolic genes, and we observe that overexpression of RNR subunits alone is not sufficient to re-sensitize arrested cells to ferroptosis, perhaps due to the absence of upstream precursors that would allow RNR to operate at full capacity

Brakedal B, Dolle C, Riber F, et al

Maca's efficacy in addressing sexual dysfunction, particularly when induced by medications or chronic illness, is one of its most well-documented clinical applications

Future research should focus on integrating microbiome-based precision medicine into AF care to bridge the evidence gap and improve patient outcomes