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Experimental studies have reported: reduced adiposity improved insulin sensitivity increased energy expenditure favorable metabolic changes However: these findings have not yet been confirmed by large human trials

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AOD-9604 is a synthetic fragment of human growth hormone that selectively stimulates fat metabolism without significantly affecting blood glucose or IGF-1

Progressive reduction in body weight after treatment with the amylin analog pramlintide in obese subjects: a phase 2, randomized, placebo-controlled, dose-escalation study