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TRPM2 TRPM2 has MHR1-4 with the IQ-motif at the large N -terminus, conserved six transmembrane segment (S1-S6) regions, and a pore-forming loop domain between S5 and S6 as well as the C -terminus composed of the TRP helix containing TRP box1 and TRP box2, a coiled-coil domain (CCD), and a unique enzymatic NUDT9 homology (NUDT9-H) domain (Figure 1)

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The proportions of indeterminate phase 1, 2, 3, and 4 were 5.6%, 3.2%, 48.0%, and 43.2%, respectively