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A 2007 study published in Chemical Research in Toxicology has found that increased exposure to lead may increase the risk of thrombotic events ( 22 )

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Cladribine, gemcitabine, lovastatin, and tamoxifen overall have lower IC 50 than the NO-based drugs, which are part of a few cancer and melanoma clinical trials (NCT00060710, NCT05502900) and pronouncedly reduced viability in both, metastatic and therapy-resistant melanoma cell lines (see Supplementary File 1)