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The compounds themselves accept electrons to generate ROS and cause oxidative stress

Microbes Infect 16:104113 Bonnemain C, Raynaud C, Rglier-Poupet H, Dubail I, Frehel C, Lety MA, Berche P, Charbit A (2004) Differential roles of multiple signal peptidases in the virulence of Listeria monocytogenes

Intracellularly, copper buffering by molecules such as GSH and metallothionein (MT) prevents ROS generation via Fenton reactions [20]

As a corollary to omics studies, large clinical data analyses and artificial intelligence (AI) networks for analyzing large scale, global patient population data on low back pain are important disciplines that have garnered much interest in recent years and continue to advance with the advent of more sophisticated analysis methods