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Aging, environmental toxins, and stress can increase your bodys demand for antioxidants beyond what a typical diet can provide, which is why many people choose to supplement.

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Lippincott, Williams and Wilkins, 2003

Anytime you introduce a novel peptide sequence into a biological system, there is a non-zero risk that the immune system could misidentify it, leading to an unwanted inflammatory cascade or even a targeted autoimmune reaction