glutathione synthetase deficiency oxoproline

glutathione synthetase deficiency oxoproline The Case | Severe high-anion gap metabolic acidosis What is pyroglutamic acid (5‑oxoproline)?

Name: glutathione synthetase deficiency oxoproline The Case | Severe high-anion gap metabolic acidosis What is pyroglutamic acid (5‑oxoproline)?
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What is pyroglutamic acid (5oxoproline)? Pyroglutamic Acidemia: An Underrecognized and Underdiagnosed Cause of High Anion Gap Metabolic Acidosis A Case Report and Review of Literature Cureus 5Oxoprolinase deficiency: report of the first human OPLAH mutation Almaghlouth 2012 Clinical Genetics Wiley Online Library Impaired Glutathione Synthesis in Neurodegeneration

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Chen Y, Peng X, Feng Z, Zhang L, Bai J, Li Y, et al

sita, sitagliptin

Studies show that interleukin-2-dependent functions including T-cell proliferation, CD8+ T-cell blast generation, cytotoxic T-cell activity, and natural killer cell function are particularly sensitive to glutathione depletion