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If the off-period is meant to let the GH axis return to baseline, switching to another GH secretagogue defeats the purpose entirely

The cardiovascular, bone density, and cognitive benefits typically outweigh the risks for this population under proper physician supervision

However, chronic alcohol exposure has been shown to significantly reduce BDNF levels in various brain regions, including the hippocampus and prefrontal cortex, which are critical for mood regulation

It is the peptide with the widest documented genomic modulation spectrum, which explains the apparent diversity of its effects (skin, hair, healing, anti-ageing)