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Device preparation The fluidic channels were fabricated using a CO 2 laser cutter machine (100 W, CMA-1390 Yueming laser, Dongguan, China) on transparent sheets of polymethyl methacrylate (PMMA) and polyvinyl chloride (PVC, thickness = 100 m, GBC) and double-sided pressure sensitive adhesive (PSA, thickness, =80 m, Flexcon, Massachusetts, USA)

Additionally, recent research suggests a potential correlation between the intensity of aerobic exercise and cognitive maintenance in individuals with mild cognitive impairment (MCI) and AD dementia (246)

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