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One day after seeding, the cells were treated with either 50 nM MitoQ, 100 nM MitoQ, 10 M retinoic acid or vehicle, and incubated 37C for 7 days

(Outlines contraindications for niacin therapy, including active peptic ulcer disease, active liver disease with elevated enzymes, hypersensitivity to niacin, and arterial bleeding, as well as monitoring recommendations for blood pressure, glucose, uric acid, etc., due to niacins systemic effects)