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Given the paternal epigenome provides a number of key regulatory features that direct embryonic development, including DNA imprinting, non-coding RNAs, and histone modifications, precise epigenetic integrity of sperm may play a role in regulating mitochondrial activity and embryonic potential (Fig

Arch Biochem Biophys 317:315323 Stoyanovsky DA, Goldman R, Jonnalagadda SS, Day BW, Claycamp HG, Kagan VE (1996) Detection and characterization of the electron paramagnetic resonance-silent glutathionyl-5, 5-dimethyl-1-pyrroline N-oxide adduct derived from redox cycling of phenoxyl radicals in model systems and HL-60 cells

have shown that H 2 S can similarly quench NO to form a novel nitrosothiol compound in vitro