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Intramuscular injection should be used only when this route of administration is necessary, and repeated injections at the same site should be avoided

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The striking loss of acini upon ablation of SOX2 + cells further confirmed that these are the sole progenitors for the acinar lineage in the SLG and is consistent with a recent report demonstrating pancreas acinar cells are not equipotent but contain a subset of progenitors (Wollny et al , 2016)