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This process is exemplified by dramatic, aged-associated increases in aneuploidy rates, and a concomitant elevation in the risk of miscarriage and birth defects 2,3,4,5

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Light exposure is a secondary but real concern: ultraviolet light can break down aromatic amino acid residues over time, which is why storing vials in their original container, away from direct light, is standard practice rather than an optional precaution

In hypercholesterolemic rats, naringin treatment attenuates vascular OS and endothelial dysfunction by reducing the protein expression of lipoprotein receptor-1, NADPH oxidase subunits, and iNOS [286]