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Cancer cells shift from normal OXPHOS to glycolysis metabolism to obtain a faster ATP production rate, maintain redox balance and synthesize nucleic acids, proteins and fatty acids

Mirvetuximab Soravtansine in FR-Positive, Platinum-Resistant Ovarian Cancer

doi: 10.1021/acschembio.5b00900 55 SchilstraMJVeldinkGAVliegenthartJF

We get people saying, Oh I dont need naloxone because I dont use fentanyl, and our team is able to say, Well, our surveillance data actually suggests there might be fentanyl in your methamphetamine or whatever it is. Nationally, both drugs are increasingly a factor in fatal overdoses: Synthetic opioids such as fentanyl contributed to 68% of overdose deaths in this years CDC data, up from 48% in 2019