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Compatibility: Use only within research protocols that follow your labs SOPs and local regulations

Patients were randomly assigned (1:1) to receive either nivolumab (3 mg/kg every 2 weeks) and a dacarbazine-matched placebo (every 3 weeks) or dacarbazine (1,000 mg/m2 every 3 weeks with a nivolumab-matched placebo every 2 weeks)

Common side effects may include : Nausea (especially at higher doses) Facial flushing or warmth Headache Injection site irritation Transient increase in blood pressure These effects are usually mild and resolve within hours

The functions of both Melanotan 1 and 2 are very similar, but the way they work is different