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Zhongyin, Z., Wei, W., Juan, X

M., Pfau, S

In radioresistant GSCs, IR enhances H3K27ac enrichment at the CD47 promoter through HDAC7-dependent mechanisms, leading to increased CD47 expression and suppression of macrophage-mediated phagocytosis, thereby promoting immune evasion after radiotherapy (Sun et al., 2024b)

Aging is the primary risk factor for most neurodegenerative diseases, and one in 10 individuals aged more than 65 years manifest symptoms of AD and its prevalence continues to advance with increasing age