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10.1023/B:BIOP.0000033439.34635.a6 48 De TullioM

Also, the hyperphosphorylation of the microtubule associated protein Tau facilitates its aggregation and formation of neurofibrillary tangles (NFTs), which are involved in synaptic disruption and neurodegeneration in Alzheimers disease (Lane et al., 2018)

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In this section, we review the findings of translational studies documenting the development of novel bioactive agents such as the oncolytic virus, the small extracellular vesicles (sEV), and nanoparticles (NPs) for the treatment of GBM ( Figure 3 and Table 2 )