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10.1158/0008-5472.CAN-08-1677 [DOI] [PMC free article] [PubMed] [Google Scholar] Smith R

Pelusi et al., 2016)

Can repeat cycles depending on response, but not recommended for indefinite continuous use

2.1 Botanical source The French maritime pine bark extract Pycnogenol is produced from the outer protective bark of the French Pinus pinaster Aiton, subspecies atlantica , which is particularly resistant against salt and frost