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Role of redox metabolism in sleep homeostasis It is well-documented that during prolonged sleep deprivation, ROS production is elevated in multiple species and in multiple organs including different regions of the brain (hippocampus, frontal cortex, cerebellum, neocortex), liver, heart, gut, and skeletal muscle (Kempf et al

Reiter RJ, Rosales-Corral SA, Tan D-X, Acuna-Castroviejo D, Qin L, Yang S-F, et al

In these countries, plant extracts have been used to treat various diseases, including epilepsy