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Aberrant DNA methylation patterns have been identified in patients with HT, leading to gene silencing and altered expression of genes regulating the immune response, along with hypermethylation of specific CpG sites

Lead Researcher Spotlight Professor Frank Ng, PhD Department of Biochemistry and Molecular Biology Monash University, Melbourne, Australia Professor Frank Ng led the pioneering research team that developed AOD-9604 in the 1990s as part of efforts to create a targeted anti-obesity therapeutic derived from human growth hormone

The four peptides work synergistically. The components are associated with different proposed pathways

Ysphaneendramallimoggala et al