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Shortcomings of compression therapy include low compliance due to discomfort and inconvenience, as well as an inability to address the underlying disease process (Zhan 2014)

In direct comparison, GHK-Cu improved collagen production in 70% of treated women, compared to 50% with vitamin C cream and just 40% with retinoic acid

Rokkas, T., Pistiolas, D., Sechopoulos, P., Robotis, I

Hence, we have limited flexibility in establishing the performance threshold since we are restricted to the data we have available from the prior period