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10.1111/jcmm.16193 89 Lpez-BarneoJ.Ortega-SenzP

By that time two types of in vitro RBC vesiculations had already been discovered as laboratory phenomena: Allan and coworkers had characterized vesicles released from RBC incubated with Ca 2+ and ionophore (Allan and Michell, 1977) and Lutz and coworkers had studied vesicles released from ATP-depleted RBC (Lutz et al., 1977)

Ferroptosis, first proposed by Stockwells group in 2012, is an iron-dependent modality of RCD and characterized by lipid peroxide accumulation, which leads to oxidative damage to cell membranes, and differs from other forms of RCD in several ways (Dixon et al., 2012)

In future articles, I will discuss other important functions of vitamin B12 , causes of vitamin B12 deficiency, and treatments to get your levels optimized